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KMID : 0614620110570020100
Korean Journal of Gastroenterology
2011 Volume.57 No. 2 p.100 ~ p.114
Guidelines for the Treatment of Constipation
Park Moo-In

Shin Jeong-Eun
Myung Seung-Jae
Huh Kyu-Chan
Choi Chang-Hwan
Jung Sung-Ae
Choi Suck-Chei
Sohn Chong-Il
Choi Myung-Gyu
Abstract
While constipation is a common symptom in Korea, there are no existing treatment guidelines. Although constipation may occur as a result of organic cause, there is no obstructive mucosal or structural cause in the vast majority of patients with constipation. The present paper deals with only the management of functional constipation: lifestyle changes; bulking agents and stool softeners; osmotic agents; stimulant laxatives; prokinetics; biofeedback and surgical treatments. Exercise and dietary fiber are helpful in some patients with constipation. Laxatives including bulking agents, stool softeners, osmotic agents, and stimulant laxatives have been found to be more effective than placebo at relieving symptoms of constipation. New enterokinetic agents that affect peristalsis through selective interaction with 5-hydroxytryptamine-4 receptors can be effective in patients with constipation who cannot get adequate relief from current laxatives. Biofeedback can relieve symptoms in selected patients with pelvic floor dyssynergia. Surgical treatments can be helpful in some patients with refractory constipation.
KEYWORD
Constipation, Treatment, Guideline
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